基因名 |
PPIA |
英文全称 |
peptidylprolyl isomerase A |
别称 |
Cyclophilin A, Cyclosporin A binding protein, CYPA, CYPH, PPIA, PPIase A, Rotamase A |
中文名称 |
肽基脯氨酸顺反式异构酶A |
Uniprot |
P62937 |
GeneID |
5478 |
交叉反应(推测) |
Human Mouse Rat (Bovine Pig Rabbit Monkey Gorilla Macaque) |
氨基酸大小 |
18kDa |
表达氨基酸 |
1-165aa |
Background |
This gene encodes a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family.PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins.The encoded protein is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression.The protein can also interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions.Multiple pseudogenes that map to different chromosomes have been reported. |
Application |
Immunology research |
Derived from |
E.coli |
Purification |
NI-NTA affinity purification |
Formulation |
Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0. |
Shipping |
The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below. |
Storage |
Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years. |
Reconstitution |
Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Purity |
Purity≥85% as determined by reducing SDS-PAGE. |
规格 |
10ug 50ug 100ug 1mg |