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| 基因名 | TIMP1 |
| 英文全称 | TIMP metallopeptidase inhibitor 1 |
| 别称 | CLGI, Collagenase inhibitor, EPA, EPO, FLJ90373, HCI, Metalloproteinase inhibitor 1, TIMP, TIMP 1, TIMP1 |
| 中文名称 | 金属肽酶抑制剂1 |
| Uniprot | P01033 |
| GeneID | 7076 |
| 交叉反应(推测) | Human Mouse Rat (Bovine Pig Sheep Dog Rabbit Horse Macaque Gorilla) |
| 氨基酸大小 | 23kDa |
| 表达氨基酸 | 1-207aa |
| Background | This gene belongs to the TIMP gene family.The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix.In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function.Transcription of this gene is highly inducible in response to many cytokines and hormones.In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females.This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. |
| Application | Immunology research |
| Derived from | E.coli |
| Purification | NI-NTA affinity purification |
| Formulation | Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0. |
| Shipping | The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| Storage | Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years. |
| Reconstitution | Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Purity | Purity≥85% as determined by reducing SDS-PAGE. |
| 规格 | 10ug 50ug 100ug 1mg |