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| 基因名 | CDK5 |
| 英文全称 | cyclin-dependent kinase 5 |
| 别称 | CDK5, Cell division protein kinase 5, cyclin dependent kinase 5, PSSALRE, TPKII catalytic subunit |
| 中文名称 | 细胞周期依赖性蛋白激酶5 |
| Uniprot | Q00535 |
| GeneID | 1020 |
| 交叉反应(推测) | Human Mouse Rat (Bovine Fruit fly) |
| 氨基酸大小 | 33kDa |
| 表达氨基酸 | 1-292aa |
| Background | This gene encodes a proline-directed serine/threonine kinase that is a member of the cyclin-dependent kinase family of proteins.Unlike other members of the family, the protein encoded by this gene does not directly control cell cycle regulation.Instead the protein, which is predominantly expressed at high levels in mammalian postmitotic central nervous system neurons, functions in diverse processes such as synaptic plasticity and neuronal migration through phosphorylation of proteins required for cytoskeletal organization, endocytosis and exocytosis, and apoptosis.In humans, an allelic variant of the gene that results in undetectable levels of the protein has been associated with lethal autosomal recessive lissencephaly-7.Alternative splicing results in multiple transcript variants. |
| Application | Immunology research |
| Derived from | E.coli |
| Purification | NI-NTA affinity purification |
| Formulation | Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0. |
| Shipping | The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| Storage | Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years. |
| Reconstitution | Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Purity | Purity≥85% as determined by reducing SDS-PAGE. |
| 规格 | 10ug 50ug 100ug 1mg |