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| 基因名 | ERK1/ERK2 |
| 英文全称 | Mitogen-activated protein kinase 1 |
| 别称 | ERK, ERK2, MAPK2, p41mapk, PRKM1, PRKM2 |
| 中文名称 | 丝裂原活化蛋白激酶1；丝裂原活化蛋白激酶2 |
| Uniprot | P28482 |
| GeneID | 5594 |
| 交叉反应(推测) | Human Mouse Rat (Bovine Monkey Gorilla) |
| 氨基酸大小 | 41kDa |
| 表达氨基酸 | 1-360aa |
| Background | The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER).This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro.This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair.This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
| Application | Immunology research |
| Derived from | E.coli |
| Purification | NI-NTA affinity purification |
| Formulation | Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0. |
| Shipping | The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| Storage | Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years. |
| Reconstitution | Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Purity | Purity≥85% as determined by reducing SDS-PAGE. |
| 规格 | 10ug 50ug 100ug 1mg |