微信小陈
微信小章
产品简介
购买须知
| 基因名 | GCLC |
| 英文全称 | glutamate-cysteine ligase |
| 别称 | Gamma ECS, GCLC, GCS, GCS heavy chain, GLCL, GLCLC |
| 中文名称 | 谷氨酸-半胱氨酸连接酶 |
| Uniprot | P48506 |
| GeneID | 2729 |
| 交叉反应(推测) | Human Mouse Rat (Fruit fly) |
| 氨基酸大小 | 29kDa |
| 表达氨基酸 | 1-253aa |
| Background | Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis.The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit.This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21.Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction |
| Application | Immunology research |
| Derived from | E.coli |
| Purification | NI-NTA affinity purification |
| Formulation | Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0. |
| Shipping | The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| Storage | Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years. |
| Reconstitution | Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Purity | Purity≥85% as determined by reducing SDS-PAGE. |
| 规格 | 10ug 50ug 100ug 1mg |