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| 基因名 | PLAU |
| 英文全称 | Urokinase-type plasminogen activator |
| 别称 | ATF;PLAU;U plasminogen activator;uPA;URK |
| 中文名称 | 尿激酶型纤溶酶原激活剂 |
| Uniprot | P00749 |
| GeneID | 5328 |
| 交叉反应(推测) | Human Mouse Rat (Rabbit Bovine Chicken Gorilla Pig) |
| 表达氨基酸 | 82-431aa |
| Application | Immunology research |
| Derived from | E.coli |
| Purification | NI-NTA affinity purification |
| Formulation | Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0. |
| Shipping | The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| Storage | Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years. |
| Reconstitution | Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Purity | Purity≥85% as determined by reducing SDS-PAGE. |
| 氨基酸大小 | 39kDa |
| Background | This gene encodes a secreted serine protease that converts plasminogen to plasmin.The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains.These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase-type plasminogen activator (HMW-uPA).HMW-uPA can be further processed into the catalytically active low molecular weight urokinase-type plasminogen activator (LMW-uPA).This low molecular weight form does not bind to the urokinase-type plasminogen activator receptor.Mutations in this gene may be associated with Quebec platelet disorder and late-onset Alzheimers disease.Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. |
| 规格 | 10ug 50ug 100ug 1mg |