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| 基因名 | JNK2/MAPK9 |
| 英文全称 | mitogen-activated protein kinase 9 |
| 别称 | c Jun N terminal kinase 2, JNK 55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, MAP kinase 9, MAPK 9, MAPK9, p54a, p54aSAPK, PRKM9, SAPK |
| 中文名称 | 丝裂原活化蛋白激酶9 |
| Uniprot | P45984 |
| GeneID | 5601 |
| 交叉反应(推测) | Human Mouse Rat (Chicken) |
| 氨基酸大小 | 42kDa |
| 表达氨基酸 | 55-424aa |
| Background | The protein encoded by this gene is a member of the MAP kinase family.MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development.This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli.It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway.This gene and MAPK8 are also known as c-Jun N-terminal kinases.This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells.Studies of this genes mouse counterpart suggest a key role in T-cell differentiation.Several alternatively spliced transcript variants encoding distinct isoforms have been reported. |
| Application | Immunology research |
| Derived from | E.coli |
| Purification | NI-NTA affinity purification |
| Formulation | Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0. |
| Shipping | The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| Storage | Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years. |
| Reconstitution | Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Purity | Purity≥85% as determined by reducing SDS-PAGE. |
| 规格 | 10ug 50ug 100ug 1mg |