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| 基因名 | NAE1 |
| 英文全称 | NEDD8 activating enzyme E1 subunit 1 |
| 别称 | A 116A10.1, APP BP1, APPBP1, HPP1, NAE1, Proto oncogene protein 1, ula 1 |
| 中文名称 | NEDD8活化酶E1调节亚基 |
| Uniprot | Q13564 |
| GeneID | 8883 |
| 交叉反应(推测) | Human Mouse Rat (Chicken Monkey) |
| 氨基酸大小 | 40kDa |
| 表达氨基酸 | 185-534aa |
| Background | This gene is located in the pseudoautosomal region 1 (PAR1) of X and Y chromosomes.It was earlier identified as a gene with similarity to Ac transposable elements, however, was found not to have transposase activity.Later studies show that this gene product is localized in the nucleus and functions as a transcription factor.It binds to DNA elements found in the promoter regions of several genes related to cell proliferation, such as histone H1, hence may have a role in regulating genes related to cell proliferation.Alternatively spliced transcript variants with different 5 untranslated region have been found for this gene. |
| Application | Immunology research |
| Derived from | E.coli |
| Purification | NI-NTA affinity purification |
| Formulation | Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0. |
| Shipping | The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| Storage | Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years. |
| Reconstitution | Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Purity | Purity≥85% as determined by reducing SDS-PAGE. |
| 规格 | 10ug 50ug 100ug 1mg |