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| 基因名 | IDH3B |
| 英文全称 | isocitrate dehydrogenase 3 (NAD+) beta |
| 别称 | RP46 |
| 中文名称 | 异柠檬酸脱氢酶3 (NAD+) β |
| Uniprot | O43837 |
| GeneID | 3420 |
| 交叉反应(推测) | Human Mouse Rat (Bovine Pig Monkey Gorilla) |
| 氨基酸大小 | 38kDa |
| 表达氨基酸 | 48-383aa |
| Background | Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate.These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+).Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic.NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle.Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit.The protein encoded by this gene is the beta subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase.Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
| Application | Immunology research |
| Derived from | E.coli |
| Purification | NI-NTA affinity purification |
| Formulation | Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0. |
| Shipping | The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| Storage | Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years. |
| Reconstitution | Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Purity | Purity≥85% as determined by reducing SDS-PAGE. |
| 规格 | 10ug 50ug 100ug 1mg |