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| 基因名 | MAN1B1 |
| 英文全称 | Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase |
| 别称 | ERManI, MANA-ER, MRT15 |
| 中文名称 | 内质网甘露糖寡糖1,2-α-甘露糖苷酶 |
| Uniprot | Q9UKM7 |
| GeneID | 11253 |
| 交叉反应(推测) | Human Mouse Rat |
| 氨基酸大小 | 40kDa |
| 表达氨基酸 | 359-698aa |
| Background | This gene encodes an enzyme belonging to the glycosyl hydrolase 47 family.This enzyme functions in N-glycan biosynthesis, and is a class I alpha-1,2-mannosidase that specifically converts Man9GlcNAc to Man8GlcNAc isomer B.It is required for N-glycan trimming to Man5-6GlcNAc2 in the endoplasmic-reticulum-associated degradation pathway.Mutations in this gene cause autosomal-recessive intellectual disability.Alternative splicing results in multiple transcript variants.A related pseudogene has been identified on chromosome 11. |
| Application | Immunology research |
| Derived from | E.coli |
| Purification | NI-NTA affinity purification |
| Formulation | Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0. |
| Shipping | The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| Storage | Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years. |
| Reconstitution | Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Purity | Purity≥85% as determined by reducing SDS-PAGE. |
| 规格 | 10ug 50ug 100ug 1mg |