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| 基因名 | PSMC4 |
| 英文全称 | proteasome (prosome, macropain) 26S subunit, ATPase, 4 |
| 别称 | MB67 interacting protein, MIP224, PSMC4, S6, Tat binding protein 7, TBP 7, TBP7 |
| 中文名称 | 蛋白酶体26S亚基6B |
| Uniprot | P43686 |
| GeneID | 5704 |
| 交叉反应(推测) | Human Mouse Rat (Bovine Monkey) |
| 氨基酸大小 | 43kDa |
| 表达氨基酸 | 1-388aa |
| Background | The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator.The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits.The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits.Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway.This gene encodes a member of the triple-A family of ATPases that is a component of the 19S regulatory subunit and plays a role in 26S proteasome assembly.The encoded protein interacts with gankyrin, a liver oncoprotein, and may also play a role in Parkinsons disease through interactions with synphilin-1.Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene |
| Application | Immunology research |
| Derived from | E.coli |
| Purification | NI-NTA affinity purification |
| Formulation | Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0. |
| Shipping | The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| Storage | Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years. |
| Reconstitution | Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Purity | Purity≥85% as determined by reducing SDS-PAGE. |
| 规格 | 10ug 50ug 100ug 1mg |