基因名 |
CDK9 |
英文全称 |
cyclin-dependent kinase 9 |
别称 |
C 2k, CDC2L4, CDK9, Cell division protein kinase 9, CTK1, cyclin dependent kinase 9, PITALRE, TAK |
中文名称 |
细胞周期依赖蛋白激酶9 |
Uniprot |
P50750 |
GeneID |
1025 |
交叉反应(推测) |
Human Mouse Rat (Bovine Zebrafish Chicken) |
氨基酸大小 |
43kDa |
表达氨基酸 |
1-372aa |
Background |
The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family.CDK family members are highly similar to the gene products of S.cerevisiae cdc28, and S.pombe cdc2, and known as important cell cycle regulators.This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II.This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K.HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS. |
Application |
Immunology research |
Derived from |
E.coli |
Purification |
NI-NTA affinity purification |
Formulation |
Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0. |
Shipping |
The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below. |
Storage |
Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years. |
Reconstitution |
Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Purity |
Purity≥85% as determined by reducing SDS-PAGE. |
规格 |
10ug 50ug 100ug 1mg |