基因名 |
FAK |
英文全称 |
Protein tyrosine kinase 2 |
别称 |
PTK2; FADK; FAK; FAK1; FRNK; PPP1R71; p125FAK; pp125FAK; focal adhesion kinase 1 |
中文名称 |
粘附斑激酶 |
Uniprot |
Q05397 |
GeneID |
5747 |
交叉反应(推测) |
Human Mouse Rat (Chicken) |
氨基酸大小 |
34kDa |
表达氨基酸 |
381-680aa |
Background |
This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents.The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies.Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix.Several transcript variants encoding different isoforms have been found for this gene. |
Application |
Immunology research |
Derived from |
E.coli |
Purification |
NI-NTA affinity purification |
Formulation |
Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0. |
Shipping |
The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below. |
Storage |
Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years. |
Reconstitution |
Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Purity |
Purity≥85% as determined by reducing SDS-PAGE. |
规格 |
10ug 50ug 100ug 1mg |