基因名 |
PARP11 |
英文全称 |
Protein mono-ADP-ribosyltransferase PARP11 |
别称 |
C12orf6, PARP 11, PARP11 |
中文名称 |
蛋白质单ADP-核糖基转移酶PARP11 |
Uniprot |
Q9NR21 |
GeneID |
57097 |
交叉反应(推测) |
Human Mouse Rat (Bovine Zebrafish) |
氨基酸大小 |
40kDa |
表达氨基酸 |
1-338aa |
Background |
This gene encodes the protein elongin A, which is a subunit of the transcription factor B (SIII) complex.The SIII complex is composed of elongins A/A2, B and C.It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units.Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits.Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C.The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. |
Application |
Immunology research |
Derived from |
E.coli |
Purification |
NI-NTA affinity purification |
Formulation |
Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0. |
Shipping |
The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below. |
Storage |
Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years. |
Reconstitution |
Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Purity |
Purity≥85% as determined by reducing SDS-PAGE. |
规格 |
10ug 50ug 100ug 1mg |