| 基因名 | PARP11 |
| 英文全称 | Protein mono-ADP-ribosyltransferase PARP11 |
| 别称 | C12orf6, PARP 11, PARP11 |
| 中文名称 | 蛋白质单ADP-核糖基转移酶PARP11 |
| Uniprot | Q9NR21 |
| GeneID | 57097 |
| 交叉反应(推测) | Human Mouse Rat (Bovine Zebrafish) |
| 氨基酸大小 | 40kDa |
| 表达氨基酸 | 1-338aa |
| Background | This gene encodes the protein elongin A, which is a subunit of the transcription factor B (SIII) complex.The SIII complex is composed of elongins A/A2, B and C.It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units.Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits.Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C.The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. |
| Application | Immunology research |
| Derived from | E.coli |
| Purification | NI-NTA affinity purification |
| Formulation | Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0. |
| Shipping | The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| Storage | Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years. |
| Reconstitution | Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Purity | Purity≥85% as determined by reducing SDS-PAGE. |
| 规格 | 10ug 50ug 100ug 1mg |