基因名 |
PTPN7 |
英文全称 |
protein tyrosine phosphatase, non-receptor type 7 |
别称 |
BPTP 4, HEPTP, LC PTP, LPTP, PTPN7, PTPNI |
中文名称 |
非受体7型蛋白酪氨酸磷酸酶 |
Uniprot |
P35236 |
GeneID |
5778 |
交叉反应(推测) |
Human Mouse Rat |
氨基酸大小 |
41kDa |
表达氨基酸 |
1-350aa |
Background |
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family.PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation.This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells.The non-catalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities.This PTP was shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway.Multiple alternatively spliced transcript variants have been found for this gene. |
Application |
Immunology research |
Derived from |
E.coli |
Purification |
NI-NTA affinity purification |
Formulation |
Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0. |
Shipping |
The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below. |
Storage |
Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years. |
Reconstitution |
Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Purity |
Purity≥85% as determined by reducing SDS-PAGE. |
规格 |
10ug 50ug 100ug 1mg |