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| 基因名 | COXIV |
| 英文全称 | cytochrome c oxidase subunit IV isoform 1 |
| 别称 | COX IV-1; COX4; COX4-1; COXIV; COXIV-1; cytochrome c oxidase subunit 4I1 |
| 中文名称 | 细胞色素C氧化酶亚基Ⅳ亚型1 |
| Uniprot | P13073 |
| GeneID | 1327 |
| 交叉反应(推测) | Human |
| 氨基酸大小 | 20kDa |
| 表达氨基酸 | 1-169aa |
| Background | Cytochrome c oxidase (COX) is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane.The complex consists of 13 mitochondrial- and nuclear-encoded subunits.The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities.The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex.This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme.It is located at the 3 of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it.Pseudogenes related to this gene are located on chromosomes 13 and 14.Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Application | Immunology research |
| Derived from | E.coli |
| Purification | NI-NTA affinity purification |
| Formulation | Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0. |
| Shipping | The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| Storage | Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years. |
| Reconstitution | Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Purity | Purity≥85% as determined by reducing SDS-PAGE. |
| 规格 | 10ug 50ug 100ug 1mg |