基因名 |
PPOX |
英文全称 |
protoporphyrinogen oxidase |
别称 |
PPOX; PPO; V290M; VP; protoporphyrinogen oxidase |
中文名称 |
原卟啉原氧化酶 |
Uniprot |
P50336 |
GeneID |
5498 |
交叉反应(推测) |
Human Mouse Rat (Bovine Pig Dog) |
氨基酸大小 |
38kDa |
表达氨基酸 |
128-477aa |
Background |
This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX.Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane.Alternatively spliced transcript variants encoding the same protein have been identified |
Application |
Immunology research |
Derived from |
E.coli |
Purification |
NI-NTA affinity purification |
Formulation |
Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0. |
Shipping |
The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below. |
Storage |
Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years. |
Reconstitution |
Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Purity |
Purity≥85% as determined by reducing SDS-PAGE. |
规格 |
10ug 50ug 100ug 1mg |