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| 基因名 | UMPS |
| 英文全称 | uridine monophosphate synthetase |
| 别称 | OMPdecase, OPRT, OPRTase, UMPS |
| 中文名称 | 尿苷单磷酸合成酶 |
| Uniprot | P11172 |
| GeneID | 7372 |
| 交叉反应(推测) | Human Mouse (Bovine Gorilla) |
| 氨基酸大小 | 38kDa |
| 表达氨基酸 | 131-480aa |
| Background | This gene encodes a uridine 5-monophosphate synthase.The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway.The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5-monophosphate.The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5-monophosphate to uridine monophosphate.Defects in this gene are the cause of hereditary orotic aciduria.Alternate splicing results in multiple transcript variants. |
| Application | Immunology research |
| Derived from | E.coli |
| Purification | NI-NTA affinity purification |
| Formulation | Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0. |
| Shipping | The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| Storage | Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years. |
| Reconstitution | Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Purity | Purity≥85% as determined by reducing SDS-PAGE. |
| 规格 | 10ug 50ug 100ug 1mg |