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| 基因名 | DSE |
| 英文全称 | dermatan sulfate epimerase |
| 别称 | dermatan sulfate epimerase, DS epimerase, DSE, DSEPI, SART 2, SART2 |
| 中文名称 | 硫酸皮肤素差向异构酶 |
| Uniprot | Q9UL01 |
| GeneID | 29940 |
| 交叉反应(推测) | Human Mouse (Bovine) |
| 氨基酸大小 | 40kDa |
| 表达氨基酸 | 609-958aa |
| Background | The protein encoded by this gene is a tumor-rejection antigen.It is localized to the endoplasmic reticulum and functions to convert D-glucuronic acid to L-iduronic acid during the biosynthesis of dermatan sulfate.This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy.Mutations in this gene cause inmusculocontractural Ehlers-Danlos syndrome.Alternative splicing results in multiple transcript variants.A related pseudogene has been identified on chromosome 9, and a paralogous gene exists on chromosome 18. |
| Application | Immunology research |
| Derived from | E.coli |
| Purification | NI-NTA affinity purification |
| Formulation | Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0. |
| Shipping | The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| Storage | Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years. |
| Reconstitution | Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Purity | Purity≥85% as determined by reducing SDS-PAGE. |
| 规格 | 10ug 50ug 100ug 1mg |