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| 基因名 | GPI |
| 英文全称 | glucose phosphate isomerase |
| 别称 | AMF; GNPI; NLK; PGI; PHI; SA-36; SA36; glucose-6-phosphate isomerase |
| 中文名称 | 葡萄糖磷酸异构酶 |
| Uniprot | P06744 |
| GeneID | 2821 |
| 交叉反应(推测) | Human Mouse (Zebrafish) |
| 氨基酸大小 | 40kDa |
| 表达氨基酸 | 1-350aa |
| Background | This gene encodes a member of the glucose phosphate isomerase protein family.The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions.In the cytoplasm, the gene product functions as a glycolytic enzyme (glucose-6-phosphate isomerase) that interconverts glucose-6-phosphate and fructose-6-phosphate.Extracellularly, the encoded protein (also referred to as neuroleukin) functions as a neurotrophic factor that promotes survival of skeletal motor neurons and sensory neurons, and as a lymphokine that induces immunoglobulin secretion.The encoded protein is also referred to as autocrine motility factor based on an additional function as a tumor-secreted cytokine and angiogenic factor.Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment.Alternative splicing results in multiple transcript variants. |
| Application | Immunology research |
| Derived from | E.coli |
| Purification | NI-NTA affinity purification |
| Formulation | Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0. |
| Shipping | The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| Storage | Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years. |
| Reconstitution | Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Purity | Purity≥85% as determined by reducing SDS-PAGE. |
| 规格 | 10ug 50ug 100ug 1mg |