基因名 |
APRT |
英文全称 |
adenine phosphoribosyltransferase |
别称 |
APRT; AMP; APRTD; adenine phosphoribosyltransferase |
中文名称 |
腺嘌呤磷酸核糖转移酶 |
Uniprot |
P07741 |
GeneID |
353 |
交叉反应(推测) |
Human Mouse Rat (Bovine Fruit fly) |
氨基酸大小 |
20kDa |
表达氨基酸 |
1-180aa |
Background |
Adenine phosphoribosyltransferase belongs to the purine/pyrimidine phosphoribosyltransferase family.A conserved feature of this gene is the distribution of CpG dinucleotides.This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP).It also produces adenine as a by-product of the polyamine biosynthesis pathway.A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis.Two transcript variants encoding different isoforms have been found for this gene. |
Application |
Immunology research |
Derived from |
E.coli |
Purification |
NI-NTA affinity purification |
Formulation |
Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0. |
Shipping |
The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below. |
Storage |
Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years. |
Reconstitution |
Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Purity |
Purity≥85% as determined by reducing SDS-PAGE. |
规格 |
10ug 50ug 100ug 1mg |