| 基因名 | APRT |
| 英文全称 | adenine phosphoribosyltransferase |
| 别称 | APRT; AMP; APRTD; adenine phosphoribosyltransferase |
| 中文名称 | 腺嘌呤磷酸核糖转移酶 |
| Uniprot | P07741 |
| GeneID | 353 |
| 交叉反应(推测) | Human Mouse Rat (Bovine Fruit fly) |
| 氨基酸大小 | 20kDa |
| 表达氨基酸 | 1-180aa |
| Background | Adenine phosphoribosyltransferase belongs to the purine/pyrimidine phosphoribosyltransferase family.A conserved feature of this gene is the distribution of CpG dinucleotides.This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP).It also produces adenine as a by-product of the polyamine biosynthesis pathway.A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis.Two transcript variants encoding different isoforms have been found for this gene. |
| Application | Immunology research |
| Derived from | E.coli |
| Purification | NI-NTA affinity purification |
| Formulation | Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0. |
| Shipping | The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| Storage | Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years. |
| Reconstitution | Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Purity | Purity≥85% as determined by reducing SDS-PAGE. |
| 规格 | 10ug 50ug 100ug 1mg |