基因名 |
RNF146 |
英文全称 |
ring finger protein 146 |
别称 |
dactylidin, dJ351K20.1, DKFZp434O1427 |
中文名称 |
环指蛋白146,E3泛素蛋白连接酶 |
Uniprot |
Q9NTX7 |
GeneID |
81847 |
交叉反应(推测) |
Human Mouse Rat (Bovine Zebrafish Monkey Gorilla) |
氨基酸大小 |
39kDa |
表达氨基酸 |
1-359aa |
Background |
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate.The encoded protein acts as a transcriptional regulator when present in a complex with other proteins.It can activate p53 transcription to promote tumor cell apoptosis in lung cancer.The protein may be involved in the differentiation of developing male germ cells.Alternative splicing of this gene results in multiple transcript variants.A related pseudogene has been identified on chromosome 5. |
Application |
Immunology research |
Derived from |
E.coli |
Purification |
NI-NTA affinity purification |
Formulation |
Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0. |
Shipping |
The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below. |
Storage |
Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years. |
Reconstitution |
Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Purity |
Purity≥85% as determined by reducing SDS-PAGE. |
规格 |
10ug 50ug 100ug 1mg |