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| 基因名 | RMND5A |
| 英文全称 | E3 ubiquitin-protein transferase RMND5A |
| 别称 | CTLH, p44CTLH, Protein RMD5 homolog A, RMD5, RMND5A |
| 中文名称 | E3泛素蛋白转移酶RMND5A |
| Uniprot | Q9H871 |
| GeneID | 64795 |
| 交叉反应(推测) | Human Mouse |
| 氨基酸大小 | 44kDa |
| 表达氨基酸 | 1-391aa |
| Background | This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases.HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation.The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel, ENaC.Single nucleotide polymorphisms in this gene may be associated with essential hypertension.Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
| Application | Immunology research |
| Derived from | E.coli |
| Purification | NI-NTA affinity purification |
| Formulation | Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0. |
| Shipping | The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| Storage | Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years. |
| Reconstitution | Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Purity | Purity≥85% as determined by reducing SDS-PAGE. |
| 规格 | 10ug 50ug 100ug 1mg |