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| 基因名 | GSTM4 |
| 英文全称 | Glutathione S-transferase Mu 4 |
| 别称 | GSTM4-4; GTM4; glutathione S-transferase Mu 4 |
| 中文名称 | 谷胱甘肽S-转移酶μ4 |
| Uniprot | Q03013 |
| GeneID | 2948 |
| 交叉反应(推测) | Human Mouse Rat (Bovine) |
| 氨基酸大小 | 26kDa |
| 表达氨基酸 | 1-218aa |
| Background | Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.Active on 1-chloro-2,4-dinitrobenzene.At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta.This gene encodes a glutathione S-transferase that belongs to the mu class.The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione.The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic.These genetic variations can change an individuals susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs.Diversification of these genes has occurred in regions encoding substrate-binding domains, as well as in tissue expression patterns, to accommodate an increasing number of foreign compounds.Multiple transcript variants, each encoding a distinct protein isoform, have been identified. |
| Application | Immunology research |
| Derived from | E.coli |
| Purification | NI-NTA affinity purification |
| Formulation | Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0. |
| Shipping | The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| Storage | Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years. |
| Reconstitution | Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Purity | Purity≥85% as determined by reducing SDS-PAGE. |
| 规格 | 10ug 50ug 100ug 1mg |