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| 基因名 | MAP3K20 |
| 英文全称 | Mitogen-activated protein kinase kinase kinase 20 |
| 别称 | MLTK,ZAK |
| 中文名称 | 丝裂原激活的蛋白激酶激酶激酶20 |
| Uniprot | Q9NYL2 |
| GeneID | 51776 |
| 交叉反应(推测) | Human Mouse Rat (Zebrafish) |
| 氨基酸大小 | 35kDa |
| 表达氨基酸 | 1-312aa |
| Background | This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM).This magnesium-binding protein forms homodimers and is located in the cytoplasm.The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells.The protein also has pro-apoptotic activity.Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
| Application | Immunology research |
| Derived from | E.coli |
| Purification | NI-NTA affinity purification |
| Formulation | Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0. |
| Shipping | The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| Storage | Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years. |
| Reconstitution | Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Purity | Purity≥85% as determined by reducing SDS-PAGE. |
| 规格 | 10ug 50ug 100ug 1mg |