宁波泰斯拓生物

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浙江省宁波市镇海区庄市街道兴庄路9号创e慧谷42号楼B幢401室
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pSP2-2

货号 TS133064
中文名称 null
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产品名称: pSP2-2
商品货号: TS133064
Designations: pSP2-2
GenBank Number:

M25824

Species: Homo sapiens, human
Depositors: EE Strehler
Vector:
Construct size (kb): 3.900000095367432
Insert:
DNA: genomic
Insert lengths(kb): 0.925000011920929
Tissue: leukocyte
Gene product: ATPase, Ca++ transporting, plasma membrane 1 PMCA1
Insert Size (kb): 0.925
Biosafety Level: 1

Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.

Shipping Information: Distributed: DNA (dried). Rehydrate with TE. (amount: 200 ng)
Comments:
Restriction digests of the clone give the following sizes (kb): BamHI--3.9; BamHI/EcoRI--3.0, 1.0; BglI--3.9; BglI/PstI--2.5, 1.5; BglI/PvuII--2.8, 1.2.
The insert contains the following restriction sites (nt from the 5 end): BalI--267; XmnI--696.
Contains a constitutively spliced exon encoding amino acids 1057-1117, the following intron, and an alternatively spliced exon which contains 2 internal donor sites.
References:

Olson S, et al. Localization of two genes encoding plasma membrane Ca2+ -transporting ATPases to human chromosomes 1q25-32 and 12q21-23. Genomics 9: 629-641, 1991. PubMed: 1674727

Strehler EE, et al. mRNAs for plasma membrane calcium pump isoforms differing in their regulatory domain are generated by alternative splicing that involves two internal donor sites in a single exon. Proc. Natl. Acad. Sci. USA 86: 6908-6912, 1989. PubMed: 2528729