产品名称: | pSP2-2 |
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商品货号: | TS133064 |
Designations: | pSP2-2 |
GenBank Number: | M25824 |
Species: | Homo sapiens, human |
Depositors: | EE Strehler |
Vector: | Construct size (kb): 3.900000095367432 |
Insert: | DNA: genomic Insert lengths(kb): 0.925000011920929 Tissue: leukocyte Gene product: ATPase, Ca++ transporting, plasma membrane 1 PMCA1 |
Insert Size (kb): | 0.925 |
Biosafety Level: | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
Shipping Information: | Distributed: DNA (dried). Rehydrate with TE. (amount: 200 ng) |
Comments: | Restriction digests of the clone give the following sizes (kb): BamHI--3.9; BamHI/EcoRI--3.0, 1.0; BglI--3.9; BglI/PstI--2.5, 1.5; BglI/PvuII--2.8, 1.2. The insert contains the following restriction sites (nt from the 5 end): BalI--267; XmnI--696. Contains a constitutively spliced exon encoding amino acids 1057-1117, the following intron, and an alternatively spliced exon which contains 2 internal donor sites. |
References: | Olson S, et al. Localization of two genes encoding plasma membrane Ca2+ -transporting ATPases to human chromosomes 1q25-32 and 12q21-23. Genomics 9: 629-641, 1991. PubMed: 1674727 Strehler EE, et al. mRNAs for plasma membrane calcium pump isoforms differing in their regulatory domain are generated by alternative splicing that involves two internal donor sites in a single exon. Proc. Natl. Acad. Sci. USA 86: 6908-6912, 1989. PubMed: 2528729 |