微信小陈
微信小章| 产品名称： | Monoclonal Anti-Influenza A virus (H1N1) H1 Hemagglutinin (HA), A/South Carolina/1/18 (1918), Clone 6B9 (produced in |
|---|---|
| 商品货号： | TS133316 |
| Classification： | Orthomyxoviridae, Influenzavirus A |
| Agent： | Monoclonal Anti-Influenza A virus (H1N1) H1 Hemagglutinin (HA), A/South Carolina/1/18 (1918), Clone 6B9 (produced in vitro) |
| Biosafety Level： | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Product Format： | frozen |
| Storage Conditions： | -20°C or colder. Repeated freeze-thaw cycles should be avoided. |
| Comments： | Antibody Class: IgG2ak The B cell hybridoma was generated by the fusion of Sp2/0 BALB/c mouse myeloma cells with splenocytes from mice immunized by DNA vaccination with a plasmid encoding the HA of influenza virus, A/South Carolina/1/1918 (H1N1) and then boosted with whole inactivated virus. |
| Name of Depositor： | A Garcia-Sastre, Mount Sinai School of Medicine |
| Source： | Mouse monoclonal antibody prepared against the H1 HA of influenza virus, A/South Carolina/1/1918 (H1N1) was purified from clone 6B9 hybridoma supernatant by protein G affinity chromatography. |
| References： | Fodor E, et al. Rescue of influenza A virus from recombinant DNA. J. Virol. 73: 9679-9682, 1999. PubMed: 10516084 Glaser L, et al. A single amino acid substitution in 1918 influenza virus hemagglutinin changes receptor binding specificity. J. Virol. 79: 11533-11536, 2005. PubMed: 16103207 Manicassamy B, et al. Protection of mice against lethal challenge with 2009 H1N1 influenza A virus by 1918-like and classical swine H1N1 based vaccines. PLoS Pathog. 6: e1000745, 2010. PubMed: 20126449 |