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微信小章| 产品名称： | M13H60 TRGJ1-J2 |
|---|---|
| 商品货号： | TS134627 |
| Designations： | M13H60 TRGJ1-J2 |
| GenBank Number： | X34034 |
| Species： | Homo sapiens, human |
| Vector： | Construct size (kb): 9.300000190734863 |
| Insert： | DNA: genomic Insert lengths(kb): 2.099999904632568 Gene product: T cell receptor, gamma cluster TCRG Alleles: J2, G1, G2, J1 |
| Insert Size (kb)： | 2.100 |
| Biosafety Level： | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Shipping Information： | Distributed: DNA (dried). Rehydrate with TE. (amount: 2 ug) |
| Comments： | Insert contains an internal EcoRI site. Restriction digests of the clone give the following sizes (kb): EcoRI--8.6, 0.74; HindIII--7.2, 2.1; SalI--9.3; PvuII--6.8, 1.4, 1.1. The HindIII (2.1 kb) and EcoRI (1.5, 5.0 kb) constant bands are from TCRGJ1; the EcoRI(7.0 kb) consant band and all other bands are from TCRGJ2. |
| References： | Lefranc MP, Rabbitts TH. Two tandemly organized human genes encoding the T-cell gamma constant-region sequences show multiple rearrangement in difference T-cell types. Nature 316: 464-466, 1985. PubMed: 2991773 Lefranc MP, et al. Rearrangement of two distinct T-cell gamma-chain variable-region genes in human DNA. Nature 319: 420-422, 1986. PubMed: 3003579 LeFranc MP, et al. Diversity and rearrangement of the human T cell rearranging gamma genes: nine germ-line variable genes belonging to two subgroups. Cell 45: 237-246, 1986. PubMed: 2938743 Lefranc MP, et al. Genetic polymorphism and exon changes of the constant regions of the human T-cell rearranging gene gamma. Proc. Natl. Acad. Sci. USA 83: 9596-9600, 1986. PubMed: 2879283 Huck S, et al. Variable region genes in the human T-cell rearranging gamma (TRG) locus: V-J junction and homology with the mouse genes. EMBO J. 7: 719-726, 1988. PubMed: 2969332 Buresi C, et al. Exon duplication and triplication in the human T-cell receptor gamma constant region genes and RFLP in French, Lebanese, Tunisian, and Black African populations. Immunogenetics 29: 161-172, 1989. PubMed: 2564370 Rabbitts TH, et al. The chromosomal location of T cell receptor genes and a T cell rearranging gene: possible correlation with specific translocations in human T-cell leukemia. EMBO J. 4: 1461-1465, 1985. PubMed: 3875483 Alexandre D, et al. Reciprocal hybrid joints demonstrate successive V - J rearrangements on the same chromosome in the human TCR gamma locus. Int. Immunol. 3: 973-982, 1991. PubMed: 1836738 Forster A, et al. New subgroups in the human T cell rearranging Vgamma gene locus. EMBO J. 6: 1945-1950, 1987. PubMed: 2820713 |