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| 产品名称： | alpha s-A366S/G226A/E268A GSL (HA tagged alpha s)-A366S/G226A/E268A, pBN382 |
|---|---|
| 商品货号： | TS134628 |
| Designations： | alpha s-A366S/G226A/E268A GSL (HA tagged alpha s)-A366S/G226A/E268A, pBN382 |
| Species： | Rattus norvegicus, rat |
| Depositors： | HR Bourne, P Herzmark |
| Applications： | in another host, produces protein guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide 1 |
| Vector： | Construct size (kb): 5.800000190734863 |
| Insert： | DNA: cDNA Insert lengths(kb): 1.5900000333786 Gene product: guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide 1 GNAS1 Target Gene: guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide 1 |
| Insert Size (kb)： | 1.590 |
| Media： | ATCC® Medium 1227: LB Medium (ATCC medium 1065) with 50 mcg/ml ampicillin |
| Biosafety Level： | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Shipping Information： | Distributed: freeze-dried |
| Comments： | Insert encodes the following mutant form: A366S, G226A, E268A. Insert expresses a hemaglutinin tagged mutated gene in mammalian cells. Insert was derived from ATCC 63315 by introducing mutations designed to inhibit receptor-mediated hormonal activation of G(s). |
| References： | Iiri T, et al. A Gsalpha mutant designed to inhibit receptor signaling through Gs. Proc. Natl. Acad. Sci. USA 96: 499-504, 1999. PubMed: 9892662 |