产品名称: | 782 L782 |
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商品货号: | TS135054 |
Designations: | 782 L782 |
Species: | Homo sapiens, human |
Vector: | Construct size (kb): 6.199999809265137 |
Insert: | DNA: genomic Insert lengths(kb): 3.400000095367432 Gene product: DNA Segment, single copy DXS85 Alleles: A2, A1 |
Insert Size (kb): | 3.400 |
Biosafety Level: | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
Shipping Information: | Distributed: DNA (dried). Rehydrate with TE. (amount: 200 ng) |
Comments: | Restriction digests of the clone give the following sizes (kb): BamHI--3.3, 3.0; HindIII--3.4, 2.8; EcoRI--6.2; BglI--3.4, 2.9; PvuI--6.2. There is tight linkage between DXS197 and DXS85 (theta = 0, LOD score = 4.14). The insert was isolated from a phage library derived from flow-sorted X chromosomes. |
References: | Hofker MH, et al. The X-chromosome shows less genetic variation at restriciton sites than the autosomes. Am. J. Hum. Genet. 39: 438-451, 1986. PubMed: 2876629 Bakker E, et al. Prenatal diagnosis and carrier detection of Duchenne muscular dystrophy with closely linked RFLPs. Lancet 1: 655-658, 1985. PubMed: 2858615 Schwartz CE, et al. Allan-Herndon syndrome. II. Linkage to DNA markers in Xq21. Am. J. Hum. Genet. 47: 454-458, 1990. PubMed: 2393020 Thakker RV, et al. Linkage analysis of two cloned DNA sequences, DXS197 and DXS207, in hypophosphatemic rickets families. Genomics 8: 189-193, 1990. PubMed: 1979046 Lagerstrom M, et al. Mapping of the gene for X-linked amelogenesis imperfecta by linkage analysis. Am. J. Hum. Genet. 46: 120-125, 1990. PubMed: 1967204 Hofker MH, et al. Isolation of probes detecting restriction fragment length polymorphisms from X chromosome-specific libraries: Potential use for diagnosis of Duchenne muscular dystrophy. Hum. Genet. 70: 148-156, 1985. PubMed: 2989153 |