产品名称: | pBmB2 |
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商品货号: | TS136994 |
Designations: | pBmB2 |
GenBank Number: | K01496 |
Species: | Mus musculus, mouse |
Depositors: | HR Colten |
Vector: | Construct size (kb): 5.900000095367432 |
Insert: | DNA: cDNA Insert lengths(kb): 1.5 Tissue: liver Gene product: properdin factor B Bf |
Insert Size (kb): | 1.5 |
Media: | ATCC® Medium 1273: LB medium (ATCC medium 1065) with 20 mcg/ml tetracycline |
Biosafety Level: | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
Comments: | Restriction digests of the clone give the following sizes (kb): EcoRI--6.2; HindIII--6.2; PstI--4.4, 1.4. Contains sequences encoding aa 263-739. The insert displays 83% nucleotide homology and 83% amino acid (derived) homology with human factor B; homology is greater at catalytic residues and in the amino terminal portion of the Bb fragment. |
Classification: | Eukaryota, Animalia, Metazoa, Chordata, Vertebrata, Tetrapod |
References: | Sackstein R, Colten HR. Molecular regulation of MHC class III (C4 and factor B) gene expression in mouse peritoneal macrophages. J. Immunol. 133: 1618-1626, 1984. PubMed: 6205089 Sackstein R, et al. Phylogenetic conservation of class III major histocompatibility complex antigen, factor B. Isolation and nucleotide sequencing of mouse factor B cDNA clones. J. Biol. Chem. 258: 14693-14697, 1983. PubMed: 6689022 |