产品名称: | p1E8 |
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商品货号: | TS137119 |
Designations: | p1E8 |
Species: | Homo sapiens, human |
Depositors: | WK Cavenee |
Vector: | Construct size (kb): 6.5 |
Insert: | DNA: genomic Insert lengths(kb): 2.099999904632568 Gene product: DNA Segment, single copy D13S4 Alleles: A2, A1 |
Insert Size (kb): | 2.100 |
Media: | ATCC® Medium 1227: LB Medium (ATCC medium 1065) with 50 mcg/ml ampicillin |
Biosafety Level: | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
Shipping Information: | Distributed: freeze-dried |
Comments: | Restriction digests of the clone give the following sizes (kb): HindIII--4.4, 2.1; BamHI--5.1, 1.5; AccI--1.65, 4.9. No recombination detected between pHUB8 and p1E8 in 30 Utah families. DNA marker in region of deletion of chromosome 13 to which gene predisposing to retinoblastoma has been mapped. |
References: | Cavenee W, et al. Isolation and regional localization of DNA segments revealing polymorphic loci from human chromosome 13. Am. J. Hum. Genet. 36: 10-24, 1984. PubMed: 6320640 Dryja TP, et al. Chromosome 13 homozygosity in osteosarcoma without retinoblastoma. Am. J. Hum. Genet. 38: 59-66, 1986. PubMed: 3004203 Lundberg C, et al. Loss of heterozygosity in human ductal breast tumors indicates a recessive mutation on chromosome 13. Proc. Natl. Acad. Sci. USA 84: 2372-2376, 1987. PubMed: 3031679 Leppert M, et al. A primary genetic map of chromosome 13q. Am. J. Hum. Genet. 39: 425-437, 1986. PubMed: 3464200 |