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| 产品名称： | pEFZ33 |
|---|---|
| 商品货号： | TS137522 |
| Designations： | pEFZ33 |
| Species： | Homo sapiens, human |
| Applications： | Codominant segregation of the MspI RFLP was observed in 43 three-generation families. |
| Vector： | Construct size (kb): 5.0 |
| Insert： | DNA: genomic Insert lengths(kb): 2.299999952316284 Gene product: DNA Segment, single copy D15S45 Alleles: A1, A2 |
| Insert Size (kb)： | 2.300 |
| Biosafety Level： | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Shipping Information： | Distributed: DNA (dried). Rehydrate with TE. (amount: 2 ug) |
| Comments： | Restriction digests of the clone give the following sizes (kb): BamHI--4.3; EcoRI--4.3, 0.3; HindIII--4.3, 0.2; EcoRI/HindIII--2.7, 2.0, 0.3; PstI--3.2, 1.5; consistent with deposited DNA. Codominant segregation of the MspI RFLP was observed in 43 three-generation families. Linkage has been established between D15S45 and Marfan syndrome in 17 families (theta = 0.02, LOD score = 7.318). Enzyme(s) not detecting polymorphism: MspI, TaqI, RsaI, PstI, BglII, PvuII. |
| References： | Fujimoto E, et al. Isolation and mapping of a polymorphic DNA sequence (pEFZ33) on chromosome 15 D15S45. Nucleic Acids Res. 16: 10946, 1988. PubMed: 2905042 Kainulainen K, et al. Marfan syndrome: no evidence for heterogeneity in different populations, and more precise mapping of the gene. Am. J. Hum. Genet. 49: 662-667, 1991. PubMed: 1882844 Yusuke Nakamura, personal communication |