产品名称: | phckit-171 |
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商品货号: | TS137997 |
Designations: | phckit-171 |
GenBank Number: | M16592 |
Species: | Homo sapiens, human |
Vector: | Construct size (kb): 4.400000095367432 |
Insert: | DNA: cDNA Insert lengths(kb): 1.25 Tissue: fetal brain Gene product: Hardy-Zuckerman 4 feline sarcoma viral (v-kit) oncogene homolog( Mast cell growth factor, c-kit proto-oncogene protein) W Alleles: A1, A2, B1, B2, , |
Insert Size (kb): | 1.25 |
Biosafety Level: | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
Shipping Information: | Distributed: DNA (dried). Rehydrate with TE. (amount: 200 ng) |
Comments: | Restriction digests of the clone give the following sizes (kb): EcoRI--3.7, 0.72; BamHI--3.2, 1.2; PstI--4.4; HindIII--3.5, 0.9; SalI--3.2, 1.2; NotI--uncut. Detects human genomic restriction fragments of the following sizes (kb): NotI--750, EagI--450, 225; SalI--550, 500, 300; XhoI--225, 125; NruI--greater than 2200. Insert includes some 5 untranslated sequence and the 5 end of the 4 kb gene. It encodes part of the extracellular domain of a 145 kDa membrane protein. |
References: | Hsieh CL, et al. Chromosomal localization of the gene for AA-type platelet-derived growth factor receptor (PDGFRA) in humans and mice. Cytogenet. Cell Genet. 56: 160-163, 1991. PubMed: 1711435 Yarden Y, et al. Human proto-oncogene c-kit: a new cell surface receptor tyrosine kinase for an unidentified ligand. EMBO J. 6: 3341-3351, 1987. PubMed: 2448137 |