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| 产品名称： | Human herpesvirus 1 x 2 (recombinant) |
|---|---|
| 商品货号： | TS140120 |
| Classification： | Herpesviridae, Simplexvirus |
| Deposited As： | Herpes simplex virus 1 x 2 (Recombinant) |
| Agent： | Human herpesvirus 1 x 2 (recombinant) |
| Strain： | D5E1 |
| Applications： | NOTE: This material is cited in a U.S. and/or other Patent and may not be used to infringe the patent claims. Sexually Transmitted Disease Research |
| Biosafety Level： | 2
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Isolation： | Crossing of parental strains of HSV-1 (KOStsE6) and HSV-2 (186tsB5) |
| Product Format： | freeze-dried |
| Storage Conditions： | -60°C or colder |
| Disclosure： | This material is cited in a US or other Patent and may not be used to infringe the claims. Depending on the wishes of the Depositor, ATCC may be required to inform the Patent Depositor of the party to which the material was furnished. This material may not have been produced or characterized by ATCC. |
| Comments： | Avirulent. Provides immunity to massive challenges of wild type strains of both HSV-1 and HSV-2. Low pathogenicity. NOTE: This material is cited in a U.S. and/or other Patent and may not be used to infringe the patent claims. |
| Effect on Host： | Cytopathic effects in tissue culture |
| Recommended Host： | HEp-2 cells (ATCC CCL-23); Vero cells (ATCC CCL-81) HEp-2 cells (ATCC CCL-23); Vero cells (ATCC CCL-81) |
| Growth Conditions： | Temperature: 35°C to 37°C |
| Name of Depositor： | Institut Merieux |
| U.S. Patent： | |
| U.S. Patent Number： | |
| Source： | Crossing of parental strains of HSV-1 (KOStsE6) and HSV-2 (186tsB5) |
| References： | Roizman B, Lang MR. Vaccine and method of immunizing against herpes simplex virus (types 1 and 2). US Patent 4,554,159 dated Nov 19 1985 Morse LS, et al. Anatomy of herpes simplex virus DNA. IX. Apparent exclusion of some parental DNA arrangements in the generation of intertypic (HSV-1 X HSV-2) recombinants. J. Virol. 24: 231-248, 1977. PubMed: 198577 |