产品名称: | S12SR |
---|---|
商品货号: | TS140121 |
Designations: | S12SR |
GenBank Number: | X03437 |
Species: | Homo sapiens, human |
Vector: | Construct size (kb): 3.799999952316284 |
Insert: | DNA: genomic Insert lengths(kb): 1.200000047683716 Gene product: T cell receptor, gamma, variable region V3 TCRG |
Insert Size (kb): | 1.200 |
Biosafety Level: | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
Shipping Information: | Distributed: DNA (dried). Rehydrate with TE. (amount: 2 ug) |
Comments: | Restriction digests of the clone give the following sizes (kb): EcoRI/HindIII--2.6, 1.3; EcoRI--3.8; HindIII--3.8; BamHI--3.8; PstI--3.8. This is a probe for the T-cell receptor V gamma 1 subgroup - J gamma. The insert is a 1.2 kb SacI/EcoRI fragment isolated from lambdaS12 and containing TCRGV3 rearranged to J2. |
References: | Lefranc MP, et al. Rearrangement of two distinct T-cell gamma-chain variable-region genes in human DNA. Nature 319: 420-422, 1986. PubMed: 3003579 LeFranc MP, et al. Diversity and rearrangement of the human T cell rearranging gamma genes: nine germ-line variable genes belonging to two subgroups. Cell 45: 237-246, 1986. PubMed: 2938743 Huck S, et al. Variable region genes in the human T-cell rearranging gamma (TRG) locus: V-J junction and homology with the mouse genes. EMBO J. 7: 719-726, 1988. PubMed: 2969332 Forster A, et al. New subgroups in the human T cell rearranging Vgamma gene locus. EMBO J. 6: 1945-1950, 1987. PubMed: 2820713 Marie-Paule Lefranc, personal communication |