| 产品名称: | pB24 |
|---|---|
| 商品货号: | TS143645 |
| Designations: | pB24 |
| Species: | Homo sapiens, human |
| Vector: | Construct size (kb): 4.650000095367432 |
| Insert: | DNA: genomic Insert lengths(kb): 0.449999988079071 Gene product: DNA Segment, single copy DXS67 Alleles: B1, B2 |
| Insert Size (kb): | 0.450 |
| Media: | ATCC® Medium 1227: LB Medium (ATCC medium 1065) with 50 mcg/ml ampicillin |
| Biosafety Level: | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Shipping Information: | Distributed: freeze-dried |
| Comments: | Restriction digests of the clone give the following sizes (kb): PvuII--2.4, 2.3; BamHI--4.65; HindIII--4.65; EcoRI--4.65; EcoRI/HindIII--4.2, 0.45. This marker shows linkage with Nance-Horan syndrome (theta = 0, LOD score = 2.74). The BstNI RFLP is also recognized by MspI, but BstNI is less subject to partials. |
| References: | Aldridge J, et al. A strategy to reveal high-frequency RFLPs along the human X chromosome. Am. J. Hum. Genet. 36: 546-564, 1984. PubMed: 6328976 Stambolian D, et al. Nance-Horan syndrome: localization within the region Xp21.1-Xp22.3 by linkage analysis. Am. J. Hum. Genet. 47: 13-19, 1990. PubMed: 1971992 Pillers DA, et al. Deletion mapping of Aland Island eye disease to Xp21 between DXS67 (B24) and Duchenne muscular dystrophy. Am. J. Hum. Genet. 47: 795-801, 1990. PubMed: 2220819 Monaco AP, et al. Localization and cloning of Xp21 deletion breakpoints involved in muscular dystrophy. Hum. Genet. 75: 221-227, 1987. PubMed: 2881877 Louis M Kunkel, personal communication |