| 产品名称: | pmetH p met H |
|---|---|
| 商品货号: | TS143795 |
| Designations: | pmetH p met H |
| Species: | Homo sapiens, human |
| Depositors: | GF Van de Woude |
| Applications: | DNA from secondary transfectants was used to isolate the clone. |
| Vector: | Construct size (kb): 5.300000190734863 |
| Insert: | DNA: genomic Insert lengths(kb): 1.600000023841858 Tissue: HOS cell line DNA transferred into NIH 3T3 cells Gene product: met proto-oncogene(hepatocyte growth factor receptor) MET Alleles: D1, D2, D1, D2, A2, B2, A2, B1, B2, A1, A1, A2, A2, B1, C1, C2, A1, A1, A1, A2, A2, C1, C2, A1 |
| Insert Size (kb): | 1.600 |
| Media: | ATCC® Medium 1227: LB Medium (ATCC medium 1065) with 50 mcg/ml ampicillin |
| Biosafety Level: | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Comments: | Restriction digests of the clone give the following sizes (kb): SalI/EcoRI--4.2, 1.25; SalI--5.5; EcoRI--5.5. NIH 3T3 cells were transformed with DNA from the osteosarcoma HOS cell line which had been treated with N-methyl-N-nitro-N-nitrosoguanidine (MNNG). DNA from secondary transfectants was used to isolate the clone. |
| References: | Park M, et al. Sequence of MET protooncogene cDNA has features characteristic of the tyrosine kinase family of growth factor receptors. Proc. Natl. Acad. Sci. USA 84: 6379-6383, 1987. PubMed: 2819873 Jacobsen SJ, et al. A clinically homogeneous group of families with facioscapulohumeral (Landouzy-Dejerine) muscular dystrophy: linkage analysis of six autosomes. Am. J. Hum. Genet. 47: 376-388, 1990. PubMed: 1975474 White R, et al. A closely linked genetic marker for cystic fibrosis. Nature 318: 382-384, 1985. PubMed: 3906407 Cooper CS, et al. Molecular cloning of a new transforming gene from a chemically transformed human cell line. Nature 311: 29-33, 1984. PubMed: 6590967 Dean M, et al. The human met oncogene is related to the tyrosine kinase oncogenes. Nature 318: 385-388, 1985. PubMed: 4069211 Lathrop GM, et al. Refined linkage map of chromosome 7 in the region of the cystic fibrosis gene. Am. J. Hum. Genet. 42: 38-44, 1988. PubMed: 2892400 Julier C, White R. Detection of a NotI polymorphism with the pmetH probe by pulsed-field gel electrophoresis. Am. J. Hum. Genet. 42: 45-48, 1988. PubMed: 2892401 |