| 产品名称: | pDP1007 |
|---|---|
| 商品货号: | TS146904 |
| Designations: | pDP1007 |
| GenBank Number: | J03134 |
| Species: | Homo sapiens, human |
| Depositors: | DC Page |
| Vector: | Construct size (kb): 4.400000095367432 |
| Insert: | DNA: genomic Insert lengths(kb): 1.299999952316284 Gene product: zinc finger protein, X-linked ZFX Alleles: A1, A2, A1, A2, |
| Insert Size (kb): | 1.300 |
| Media: | ATCC® Medium 1227: LB Medium (ATCC medium 1065) with 50 mcg/ml ampicillin |
| Biosafety Level: | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Shipping Information: | Distributed: freeze-dried |
| Comments: | Restriction digests of the clone give the following sizes (kb): HindIII--2.95, 1.35; PstI--3.8, 0.61; BamHI--4.4; EcoRI--4.4; XbaI--4.4. pDP1007 is derived from the ZFY gene in interval 1A2 of the Y chromosome but also hybridizes to the ZFX gene on Xp22.1 of the human X chromosome. This encodes a 1.2 kb open reading frame. Enzyme(s) not detecting polymorphism: BamHI, BglI, BglII, EcoRI, MspI, PstI, SstI, TaqI, XbaI. |
| References: | Page DC. Is ZFY the sex-determining gene on the human Y chromosome?. Philos. Trans. R. Soc. Lond. B Biol. Sci. 322: 155-157, 1988. PubMed: 2907799 Schneider-Gadicke A, et al. ZFX has a gene structure similar to ZFY, the putative sex determinant, and excapes X inactivation. Cell 57: 1247-1258, 1989. PubMed: 2500252 Spurdle AB, Jenkins T. pDP1007, detects an X polymorphism with HindIII in negroids at the ZFX locus. Nucleic Acids Res. 18: 3430, 1990. PubMed: 1972568 Page DC, et al. The sex-determining region of the human Y chromosome encodes a finger protein. Cell 51: 1091-1104, 1987. PubMed: 3690661 |