微信小陈
微信小章| 产品名称： | pGSM21 |
|---|---|
| 商品货号： | TS148126 |
| Designations： | pGSM21 |
| Species： | Homo sapiens, human |
| Vector： | Construct size (kb): 13.30000019073486 |
| Insert： | DNA: genomic Insert lengths(kb): 9.0 Gene product: DNA Segment, single copy, expressed D21S13 Alleles: A1, A2, E1, E2, A1, A2, E1, E2 |
| Insert Size (kb)： | 9.0 |
| Biosafety Level： | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Shipping Information： | Distributed: DNA (dried). Rehydrate with TE. (amount: 2 ug) |
| Comments： | D21S13 contains a CpG island. The insert contains SmaI (2), PvuII (4), BssHII (2), SacII (1), NotI (1), and CfoI (1) sites. Restriction digests of the clone give the following sizes (kb): EcoRI--8.5, 4.0; HindIII--13.0; PstI--4.9, 2.4, 1.7, 1.35, 0.88, 0.68; BamHI--4.0 (doublet), 2.9, 0.88; SalI--13.0. An 8.4 kb EcoRI fragment contains a methylation-free HTF (HpaII tiny fragment) island and the following restriction sites: ApaI (1), BssHII (2), SacII (2), NotI (1), XbaI (1), and KpnI (1). Isolated from the chromosome 22 library of R. Krumlauf et al. |
| References： | Stewart GD, et al. Trisomy 21 (Down syndrome): studying nondisjunction and meoitic recombination by using cytogenetic and molecular polymorphisms that span chromosome 21. Am. J. Hum. Genet. 42: 227-236, 1988. PubMed: 2893544 Owen MJ, et al. Physical mapping around the Alzheimer disease locus on the proximal long arm of chromosome 21. Am. J. Hum. Genet. 46: 316-322, 1990. PubMed: 2301399 Van Keuren ML, et al. Characterization of an unusual and complex chromosome 21 rearrangement using somatic cell genetics and cloned DNA probes. Am. J. Med. Genet. 33: 369-375, 1989. PubMed: 2529766 Leveillard T, et al. A high frequency EcoRI RFLP detected at the D21S13 locus. Nucleic Acids Res. 18: 1319, 1990. PubMed: 1969629 Stinissen P, et al. The pericentromeric 21 DNA marker pGSM21 (D21S13) contains an expressed HTF island. Genomics 7: 119-122, 1990. PubMed: 1692297 |