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微信小章| 产品名称： | Streptomyces peucetius subsp. caesius Arcamone et al. |
|---|---|
| 商品货号： | TS149260 |
| Strain Designations： | IMRU 3920 FI 186, IPV 1946 |
| Application： | Produces FCE 21424 Produces FCE 24366 Produces FCE 24367 Produces doxorubicin adriamycin Produces antineoplastic agents FCE 21424, FCE 24366 and FCE 24367 |
| Biosafety Level： | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Product Format： | freeze-dried |
| Storage Conditions： | Frozen: -80°C or colder Freeze-Dried: 2°C to 8°C Live Culture: See Propagation Section |
| Preceptrol®： | no |
| Type Strain： | no |
| Comments： | Synthase genes for daunorubicin/doxorubicin |
| Medium： | ATCC® Medium 1877: ISP Medium 1 ATCC® Medium 196: Yeast malt extract agar |
| Growth Conditions： | Temperature: 26°C
Atmosphere: Aerobic |
| Name of Depositor： | RE Gordon |
| Chain of Custody： | ATCC <-- RE Gordon <-- B. Camerino, Farmitalia FI 106 |
| References： | Cassinelli G, et al. New biosynthetic anthracyclines related to barminomycins incorporating barbiturates in their moiety. J. Antibiot. 43: 19-28, 1990. PubMed: 2307627 Arcamone F, et al. Adriamycin derivatives. US Patent 3,590,028 dated Jun 29 1971 Stutzman-Engwall KJ, Hutchinson CR. Multigene families for anthracycline antibiotic production in Streptomyces peucetius. Proc. Natl. Acad. Sci. USA 86: 3135-3139, 1989. PubMed: 2717612 |
| Cross References： | Nucleotide (GenBank) : U80222 Streptomyces peucetius ceasius flavin-binding site DnrW (dnrW) gene, complete cds. Nucleotide (GenBank) : U09844 Streptomyces peucetius caesius aklavinone C-11 hydroxylase (dnrF) gene, complete cds. |