| 产品名称: | CD-3A |
|---|---|
| 商品货号: | TS150199 |
| Designations: | CD-3A |
| GenBank Number: | X53337 |
| Species: | Mus musculus, mouse |
| Depositors: | JF Diedrich |
| Vector: | Construct size (kb): 4.900000095367432 |
| Insert: | DNA: cDNA Insert lengths(kb): 1.899999976158142 Tissue: brain Gene product: cathepsin D Ctsd |
| Insert Size (kb): | 1.900 |
| Media: | ATCC® Medium 1227: LB Medium (ATCC medium 1065) with 50 mcg/ml ampicillin |
| Biosafety Level: | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Shipping Information: | Distributed: freeze-dried |
| Comments: | Restriction digests of the clone give the following sizes (kb): EcoRI--3.0, 1.9; PstI--4.0, 0.96; BamHI--4.2, 0.46, 0.37; PvuII--2.6, 1.75, 0.46, 0.28; HindIII--5.0. The insert contains the following restriction sites (approximate kb from the 5 end): PstI--0.91; BamHI--1.13, 1.56; PvuII--1.36, 1.82. The insert extends from nt 21 to the 3 end of the published sequence and includes 16 nt of the poly(A) tail. It does not include the 5 untranslated region or sequence encoding the first 5 aa. |
| Classification: | Eukaryota, Animalia, Metazoa, Chordata, Vertebrata, Tetrapod |
| References: | Diedrich JF, et al. Nucleotide sequence of a cDNA encoding mouse cathepsin D. Nucleic Acids Res. 18: 7184, 1990. PubMed: 2263503 Diedrich JF, et al. Neuropathological changes in scrapie and Alzheimers disease are associated with increased expression of apolipoprotein E and cathepsin D in astrocytes. J. Virol. 65: 4759-4768, 1991. PubMed: 1870200 Jane F Diedrich, personal communication |