| 产品名称: | H3-8 pH3-8 |
|---|---|
| 商品货号: | TS150515 |
| Designations: | H3-8 pH3-8 |
| Species: | Homo sapiens, human |
| Vector: | Construct size (kb): 5.800000190734863 |
| Insert: | DNA: genomic Insert lengths(kb): 1.399999976158142 Gene product: retinoblastoma 1 (including osteosarcoma) RB1 Alleles: A1, A2, A1, A2 |
| Insert Size (kb): | 1.400 |
| Biosafety Level: | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Shipping Information: | Distributed: DNA (dried). Rehydrate with TE. (amount: 200 ng) |
| Comments: | Restriction digests of the clone give the following sizes (kb): HindIII--4.4, 1.4; EcoRI--5.8; EcoRI/HindIII--4.3, 1.5; SalI--5.8; SalI/EcoRI--3.8, 2.2. This probe detects heterozygous deletions in patients with bilateral and multifocal unilateral retinoblastoma. |
| References: | Dryja TP, et al. Molecular detection of deletions involving band q14 of chromosome 13 in retinoblastomas. Proc. Natl. Acad. Sci. USA 83: 7391-7394, 1986. PubMed: 2876425 Lalande M, et al. Molecular detection and differentiation of deletions in band 13q14 in human retinoblastoma. Cancer Genet. Cytogenet. 23: 151-157, 1986. PubMed: 3756834 Lalande M, et al. Isolation of human chromosome 13-specific DNA sequences cloned from flow sorted chromosomes and potentially linked to the retinoblastoma locus. Cancer Genet. Cytogenet. 13: 283-295, 1984. PubMed: 6210139 |