| 产品名称: | pKER2 |
|---|---|
| 商品货号: | TS150644 |
| Designations: | pKER2 |
| Species: | Homo sapiens, human |
| Vector: | Construct size (kb): 11.5 |
| Insert: | DNA: genomic Insert lengths(kb): 2.400000095367432 Gene product: excision repair cross-complementing rodent repair deficiency, complementation group 2(DNA excision repair protein ERCC2) ERCC2 Alleles: c, s, |
| Insert Size (kb): | 2.400 |
| Biosafety Level: | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Shipping Information: | Distributed: DNA (dried). Rehydrate with TE. (amount: 2 ug) |
| Comments: | Restriction digests of the clone give the following sizes (kb): BamHI--6.0, 3.5, 1.0; EcoRI--10.5; EcoRI/HindIII--4.8 (doublet), 0.52; KpnI--7.8, 2.4. Detect human genomic restriction fragments of the following sizes (approximate kb): EcoRI--40; NotI--250; MluI--400; ClaI (partial)--260, 200. This clone was constructed by L. Bachinski in M. Sicilianos laboratory at the University of Texas System Cancer Center, M.D. Anderson Hospital, Houston, Texas. It contains the 3 end of ERCC2. |
| References: | Saunders AM, Seldin MF. The syntenic relationship of proximal mouse chromosome 7 and the myotonic dystrophy gene region on human chromosome 19q. Genomics 6: 324-332, 1990. PubMed: 2307474 Smeets H, et al. A long-range restriction map of the human chromosome 19q13 region: close physical linkage between CKMM and the ERCC1 and ERCC2 genes. Am. J. Hum. Genet. 46: 492-501, 1990. PubMed: 2309701 Weber CA, et al. Molecular cloning and biological characterization of a human gene, ERCC2, that corrects the nucleotide excision repair defect in CHO UV5 cells. Mol. Cell. Biol. 8: 1137-1146, 1988. PubMed: 2835663 Christine A Weber, personal communication |