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微信小章| 产品名称： | LRP06 |
|---|---|
| 商品货号： | TS151107 |
| Designations： | LRP06 |
| GenBank Number： | X13916 |
| Species： | Homo sapiens, human |
| Depositors： | J Herz |
| Vector： | Construct size (kb): 8.859999656677246 |
| Insert： | DNA: cDNA Insert lengths(kb): 5.991000175476074 Tissue: liver Gene product: low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor)(apoE receptor, apolipoprotein receptor, low density lipoprotein receptor-related (LDL-receptor related), lrp) APR |
| Insert Size (kb)： | 5.991 |
| Media： | ATCC® Medium 1227: LB Medium (ATCC medium 1065) with 50 mcg/ml ampicillin |
| Biosafety Level： | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Shipping Information： | Distributed: freeze-dried |
| Comments： | Restriction digests of the clone give the following sizes (kb): XhoI/EcoRI--6.0, 2.9; EcoRI--8.9; HindIII--uncut; BamHI--6.8, 2.2; PvuII--5.8, 3.0. The insert contains the following restriction sites, in approximate kb from the 5 end: SalI--1.35; BamHI--2.24, 4.46, 4.47; PvuII--5.63, 5.80; EcoRI--5.986. Extends from nt 188 to nt 6179 of the submitted sequence, containing part of the coding sequences which extend from nt 467 to nt 14104 of the 14.896 kb cDNA. |
| References： | Herz J, et al. Surface location and high affinity for calcium of a 500-kd liver membrane protein closely related to the LDL-receptor suggest a physiological role as lipoprotein receptor. EMBO J. 7: 4119-4127, 1988. PubMed: 3266596 Myklebost O, et al. The gene for the putative apoE receptor is on chromosome 12 in the segment q13-q14. Genomics 5: 65-69, 1989. PubMed: 2548950 Strickland DK, et al. Sequence identity bwteen the alpha 2-macroglobulin receptor and low density lipoprotein receptor-related protein suggests that this molecule is a multifunctional receptor. J. Biol. Chem. 265: 17401-17404, 1990. PubMed: 1698775 Kristensen T, et al. Evidence that the newly cloned low-density-lipoprotein receptor-related protein (LRP) is the alpha-2-macroglobulin receptor. FEBS Lett. 276: 151-155, 1990. PubMed: 1702392 Joachim Herz, personal communication |