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| 产品名称： | pHGTH4 |
|---|---|
| 商品货号： | TS151763 |
| Designations： | pHGTH4 |
| Species： | Homo sapiens, human |
| Depositors： | JR Kelsoe |
| Vector： | Construct size (kb): 5.300000190734863 |
| Insert： | DNA: genomic Insert lengths(kb): 2.299999952316284 Tissue: lymphoblast GM5933 cell line Gene product: tyrosine hydroxylase TH Alleles: A1, A2 |
| Insert Size (kb)： | 2.300 |
| Media： | ATCC® Medium 1227: LB Medium (ATCC medium 1065) with 50 mcg/ml ampicillin |
| Biosafety Level： | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Shipping Information： | Distributed: freeze-dried |
| Comments： | Restriction digests of the clone give the following sizes (kb): BamHI--3.2, 2.4; BamHI/HindIII--3.2, 1.6, 0.8; EcoRI--3.8, 1.5; PstI--3.6, 0.68, 1.3; PvuI--4.0, 1.0. PstI was homoallelic for A2 in 6 subjects from Amish pedigree 110 (IMR 884) in which two other chromosome 11 RFLPs were reported linked to manic-depressive illness. Insert contains exon 10 through the 3 end of the gene, i.e. exons 10-13 including 3 untranslated sequence. |
| References： | OMalley KL, et al. Isolation and characterization of the human tyrosine hydroxylase gene: identification of 5 alternative splice sites responsible for multiple mRNAs. Biochemistry 26: 6910-6914, 1987. PubMed: 2892528 Kelsoe JR, et al. Human tyrosine hydroxylase (TH) genomic fragment (pHGTH4) identifies a PstI polymorphism. Nucleic Acids Res. 16: 7760, 1988. PubMed: 2901074 |