| 产品名称: | gp91-phox-cDNA UTR-01292, WI-7096 |
|---|---|
| 商品货号: | TS152952 |
| Designations: | gp91-phox-cDNA UTR-01292, WI-7096 |
| GenBank Number: | X04011 |
| Species: | Homo sapiens, human |
| Vector: | Construct size (kb): 4.599999904632568 |
| Insert: | DNA: cDNA Insert lengths(kb): 1.600000023841858 Tissue: HL-60 cell line (promyelocytic leukemia) Gene product: cytochrome b-245, beta polypeptide (chronic granulomatous disease)(cytochrome b-245, beta polypeptide) CGD |
| Insert Size (kb): | 1.600 |
| Biosafety Level: | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Shipping Information: | Distributed: DNA (dried). Rehydrate with TE. (amount: 200 ng) |
| Comments: | Restriction digests of the clone give the following sizes (kb): PstI--4.6; XhoI--4.6; PstI/XhoI--3.0, 1.6; EcoRI--4.6; PvuII--2.5, 2.1. The insert contains the EcoRI site at nt 1570 of the published sequence. Extends from the PstI site at nt 186 of the published sequence (5 untranslated region) through the complete coding sequence into the 3 untranslated region to the SacI site at about nt 1950. The polypeptide is encoded from nt 13 to 1728 of the final published sequence. Oriented such that transcription from the T7 promoter gives the sense strand. |
| References: | Orkin SH. Molecular genetics of chronic granulomatous disease. Annu. Rev. Immunol. 7: 277-307, 1989. PubMed: 2523713 Royer-Pokora B, et al. Cloning the gene for an inherited human disorder--chronic granulomatous disease--on the basis of its chromosomal location. Nature 322: 32-38, 1986. PubMed: 2425263 |