| 产品名称: | cSOD |
|---|---|
| 商品货号: | TS154365 |
| Designations: | cSOD |
| Species: | Homo sapiens, human |
| Depositors: | Y Groner |
| Vector: | Construct size (kb): 3.599999904632568 |
| Insert: | DNA: cDNA Insert lengths(kb): 0.6000000238418579 Tissue: fibroblast cell line SV80 Gene product: superoxide dismutase 1, soluble(superoxide dismutase, Cu-Zn) SOD1 Alleles: B1, B2 |
| Insert Size (kb): | 0.600 |
| Biosafety Level: | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Shipping Information: | Distributed: DNA (dried). Rehydrate with TE. (amount: 200 ng) |
| Comments: | Restriction digests of the clone give the following sizes (kb): PstI--3.0, 0.6; HindIII--3.6; BamHI--3.6; EcoRI--3.6; BglII--uncut. The insert contains the complete coding sequence and 3 untranslated regions of the cDNA. The clone detects mRNA of about 500 bp and 700 bp in human cells and of about 500 bp and 4.8 kb (minor) in mouse cells. The clone detects the following genomic restriction fragments (kb): EcoRI--18; BglII--5.1, 4.1; PstI--5.6, 3.6, 2.3; HindIII--14.5, 1.3, 0.8. |
| References: | Levanon D, et al. Architecture and anatomy of the chromosomal locus in human chromosome 21 encoding the Cu/Zn superoxide dismutase. EMBO J. 4: 77-84, 1985. PubMed: 3160582 Lieman-Hurwitz J, et al. Human cytoplasmic superoxide dismutase cDNA clone: a probe for studying the molecular biology of Down syndrome. Proc. Natl. Acad. Sci. USA 79: 2808-2811, 1982. PubMed: 6211674 Sherman L, et al. Nucleotide sequence and expression of human chromosome 21-encoded superoxide dismutase mRNA. Proc. Natl. Acad. Sci. USA 80: 5465-5469, 1983. PubMed: 6577438 |