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| 产品名称： | pRabGGT-A |
|---|---|
| 商品货号： | TS154407 |
| Designations： | pRabGGT-A |
| GenBank Number： | L13722 |
| Species： | Rattus norvegicus, rat |
| Depositors： | DA Andres |
| Vector： | Construct size (kb): 7.5 |
| Insert： | DNA: cDNA Insert lengths(kb): 4.5 Gene product: choroideremia(REP-1, Rab escort protein 1, tapeto-choroidal dystrophy, progressive choroidemia) CHM |
| Insert Size (kb)： | 4.5 |
| Media： | ATCC® Medium 1227: LB Medium (ATCC medium 1065) with 50 mcg/ml ampicillin |
| Biosafety Level： | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Shipping Information： | Distributed: frozen |
| Comments： | Restriction digests of the clone give the following sizes (kb): XhoI/XbaI--4.5, 2.95, 0.3 +smaller; EcoRI--3.3, 3.1, 1.6; EcoRV--6.3, 1.7; NdeI--6.4, 1.55; HindIII--4.4, 3.5. Restriction digests of the clone give the following sizes (kb): EcoRI--3.2, 2.9, 1.3; EcoRV--5.7, 1.67; NdeI--5.9, 1.475. This is the homolog of the protein which, when defective in humans, results in choroideremia (CHM). Transcription from the T7 promoter gives the sense strand. |
| References： | Andres DA, et al. cDNA cloning of component A of Rab geranylgeranyl transferase and demonstration of its role as a Rab escort protein. Cell 73: 1091-1099, 1993. PubMed: 8513495 Douglas A Andres, personal communication |