| 产品名称: | pYNZ2 |
|---|---|
| 商品货号: | TS156328 |
| Designations: | pYNZ2 |
| Species: | Homo sapiens, human |
| Depositors: | RL White |
| Vector: | Construct size (kb): 16.0 |
| Insert: | DNA: genomic Insert lengths(kb): 3.0 Gene product: DNA Segment, single copy D1S57 Alleles: A2, A3, A1 |
| Insert Size (kb): | 3.0 |
| Media: | ATCC® Medium 1227: LB Medium (ATCC medium 1065) with 50 mcg/ml ampicillin |
| Biosafety Level: | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Shipping Information: | Distributed: freeze-dried |
| Comments: | Restriction digests of the clone give the following sizes (kb): HindIII--4.5, 2.9; EcoRI--8.4, 8.4; EcoRI/HindIII--4.5, 2.6, 2.3; PstI--5.4, 4.2, 3.4, 3.0; HincII--8.4, 4.2, 3.4; consistent with deposited DNA. Codominant segregation has been demonstrated in more than 52 three-generation families. The probe appears to contain four copies of the insert. Detection of the TaqI polymorphism (alleles 10, 9, and 8 kb) was verified by CEPH. The RFLPs are detected under normal stringency (0.1X SSC). |
| References: | Bradley DG, et al. Autosomal dominant retinitis pigmentosa: exclusion of the gene from the short arm of chromosome 1 including the region surrounding the Rhesus locus. Am. J. Hum. Genet. 44: 570-576, 1989. PubMed: 2564733 Dracopoli NC, et al. The CEPH consortium linkage map of human chromosome 1. Genomics 9: 686-700, 1991. PubMed: 2037294 Nakamura Y, et al. Variable number of tandem repeat (VNTR) markers for human gene mapping. Science 235: 1616-1622, 1987. PubMed: 3029872 Nakamura Y, et al. Isolation and mapping of a polymorphic DNA sequence (pYNZ2) on chromosome 1p (D1S57). Nucleic Acids Res. 16: 4747, 1988. PubMed: 2454462 |